Lab Scope

The StopkaLab started in June 2005 in the 1st Medical Faculty at the Charles University in Prague. We are interested in basic aspects of normal and malignant hematopoiesis. The lab is supported by research grants and university research funding.

Lab members have both scientific and medical backgrounds. Bioinformaticians represent significant part of the research team. Lab is involved in research training&teaching activities. Three Lab members are also involved in medical care at Haematology clinic (faculty hospital).

The Lab team resides in the Biocev building (Vestec near Prague) and is a member of the Functional Genomics Program and utilizes mouse transgenic biology to better understand role of chromatin remodeling in hematopoiesis. The lab also participates on patient-oriented biomedical projects that are focused mostly on the pathogenesis of Myelodysplastic syndrome, myeloid leukemias, and some types of lymphoma.

Research focus:

1. transcription and chromatin remodeling factors in hematopoiesis and leukemogenesis (mouse models)

2. genetics and epigenetics of Myelodysplastic Syndromme and other hematologic tumors (patient-oriented)